Immunological reprogramming

of the liver grafts during extracorporeal machine perfusion in the period between explantation and implantation to minimize alloresponse and promote local graft acceptance.

In vivo selection of immune regulatory genes in a porcine hepatocyte transplant model
Markus Guba, Dominik Koch, Eckhard Wolf

Induction of local allograft acceptance through immune-editing during warm, oxygenated machine perfusion
Dionysios Koliogiannis, Markus Guba